Lenvatinib is administered orally once daily under current U.S. labeling. The medicine can be taken with or without food and should generally be taken at the same time each day.
The exact prescribed dose depends on the cancer being treated, whether lenvatinib is being combined with another medicine, kidney or liver function and other clinical factors.
General administration principles
- Take lenvatinib exactly as prescribed.
- Take it once daily when prescribed as a once-daily regimen.
- It may be taken with or without food under current U.S. labeling.
- Try to take it at approximately the same time each day.
- Do not independently change the dose.
- Do not stop treatment without discussing it with the treating healthcare professional.
- Report significant or persistent adverse effects promptly.
Missed dose
Current U.S. labeling states that if a missed dose cannot be taken within 12 hours, the missed dose should be skipped and the next dose taken at the usual time.
Patients should not take extra medication to compensate for a missed dose unless specifically instructed by their healthcare professional.
Capsule handling
The official prescribing information includes instructions for swallowing capsules and, when necessary, preparation of a suspension for administration. These instructions should be followed exactly as specified in the applicable product information.
Monitoring during treatment
Lenvatinib treatment commonly requires clinical and laboratory monitoring. Depending on the indication and patient, monitoring may include blood pressure, kidney function, liver function, urine protein, thyroid function, electrolytes and symptoms suggesting cardiovascular or other serious toxicity.
Storage
Storage instructions should be taken from the specific product’s package and official prescribing information.